Human Milk Glycoproteins Protect Infants Against Human Pathogens
نویسندگان
چکیده
منابع مشابه
Oligosaccharides and glycoconjugates of human milk could protect breast-fed infants against norovirus intestinal infections
Background: Noroviruses are, after rotaviruses, the most common cause of nonbacterial intestinal infections in children. It has been observed a lower incidence of norovirus gastroenteritis in breast-fed compared to formula-fed infants. Effective vaccines against noroviruses are not yet available, enhancing the interest of the protective mechanisms elicited by human milk. Human milk contains a w...
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Breast-feeding is a highly effective strategy for preventing morbidity and mortality in infancy. The human-milk glycans, which include oligosaccharides in their free and conjugated forms, constitute a major and an innate immunologic mechanism by which human milk protects breast-fed infants against infections. The glycans found in human milk function as soluble receptors that inhibit pathogens f...
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Significant benefits to infant host defense, sensory-neural development, gastrointestinal maturation, and some aspects of nutritional status are observed when premature infants are fed their mothers' own milk. A reduction in infection-related morbidity in human milk-fed premature infants has been reported in nearly a dozen descriptive, and a few quasi-randomized, studies in the past 25 years. H...
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The implementation of beneficial microorganisms for plant protection has a long history. Many rhizobia bacteria are able to influence the immune system of host plants by inducing resistance towards pathogenic microorganisms. In this report, we present a translational approach in which we demonstrate the resistance-inducing effect of Ensifer meliloti (Sinorhizobium meliloti) on crop plants that ...
متن کاملHuman milk oligosaccharides protect bladder epithelial cells against uropathogenic Escherichia coli invasion and cytotoxicity.
The invasive pathogen uropathogenic Escherichia coli (UPEC) is the primary cause of urinary tract infections (UTIs). Recurrent infection that can progress to life-threatening renal failure has remained as a serious global health concern in infants. UPEC adheres to and invades bladder epithelial cells to establish infection. Studies have detected the presence of human milk oligosaccharides (HMOs...
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ژورنال
عنوان ژورنال: Breastfeeding Medicine
سال: 2013
ISSN: 1556-8253,1556-8342
DOI: 10.1089/bfm.2013.0016